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Severe thunderstorms to rumble across the central, eastern US this week. Click for the forecast. Chevron right

Mayesville, SC

70°F
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Mayesville

South Carolina

70°
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Mayesville, SC Weather
Today WinterCast Local {stormName} Tracker Hourly 10-Day Radar MinuteCast® Monthly Air Quality Health & Activities

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Monthly

Air Quality Health & Activities

April

January February March April May June July August September October November December

2026

2025 2026 2027

10-Day

S
M
T
W
T
F
S
29
70°
28°
30
77°
43°
31
81°
48°
1
86°
54°
2
82°
55°
3
81°
57°
4
86°
54°
5
82°
64°
6
66°
45°
7
72°
43°
8
66°
46°
9
70°
36°
10
77°
39°
11
86°
45°
12
86°
48°
13
82°
50°
14
86°
55°
15
Mostly sunny and hot
91°
59°
16
Partly sunny and hot
92°
58°
17
Sunny and hot
93°
59°
18
Hot with partial sunshine
94°
64°
19
Not as warm, turning breezy
81°
45°
20
Nice with plenty of sunshine
71°
40°
21
Mostly sunny
75°
48°
22
Partly sunny
78°
53°
23
A thick cloud cover
82°
56°
24
Some rain and a thunderstorm
84°
59°
25
Mostly cloudy
81°
59°
26
A little morning rain
76°
56°
27
Mostly sunny
75°
55°
28
A shower and thunderstorm
74°
53°
29
Mostly cloudy with a shower
74°
56°
30
Rain
75°
55°
1
Partial sunshine
74°
52°
2
Clouds yielding to sun
77°
55°

Temperature Graph

°F
100° 86° 72° 58° 44° Apr
Today 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo

April Weather in Mayesville

Mayesville's April 2026 forecast shows daily high temperatures ranging from 71° to 94°, with overnight lows between 40° and 64°. The average high for April is 80° with an average low of 55°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how April weather will actually feel in Mayesville. See also: May | June | July.

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World North America United States South Carolina Mayesville

Weather Near Mayesville:

  • Columbia, SC
  • St. Andrews, SC
  • Sumter, SC
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